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To better simulate the clinical situation, a xenograft mouse model derived from PDCs with high and low expression of VRK2 was employed for further study

doi:10.1016/j.iac.2018.04.003 Sperr WR, Jordan JH, Fiegl M, et al

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View Study [3]"Coadministered Cagrilintide and Semaglutide in Adults with Overweight or Obesity" Garvey WT et al., 2025 Finding: The REDEFINE 1 Phase 3 trial showed CagriSema achieved 20.4% weight loss versus 3% with placebo over 68 weeks in 3,417 participants